The Essence of Klotho

Named after a Greek goddess of fate, Klotho is a protein each of us naturally makes. It declines with age. Klotho levels influence our cardiovascular, cognitive, and kidney health. Lower Klotho levels are associated with cellular senescence, reduced autophagy, and the overall process of aging. Restoring Klotho levels even just a little bit has broad spectrum functional implications in terms of cellular health, longevity, cholesterol, blood pressure, energy, cognition, learning, and memory.

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What is Klotho?

Klotho is a crucial anti-aging protein primarily produced in the kidneys and brain, acting as a longevity hormone that regulates mineral metabolism, reduces oxidative stress, and enhances cognitive function. It exists as both a membrane-bound receptor and a circulating protein, with higher levels correlating with improved health span, while deficiency accelerates aging, leading to kidney diseases, cardiovascular issues, and cognitive decline.